Study On Synthesis, Characterization And Medical Applications Of Zinc Nanoparticles In T.Populnea

Abstract

Nanotechnology, spanning various disciplines, encompasses applications in science and technology, particularly in the manipulation of nanoparticles ranging from 1 to 100nm in size. The leaves and figs of the locally abundant Thespesia populnea, also known as the Portia tree, were selected for nanoparticle isolation in this study. For characterization, 0.1gm of each sample was mixed thoroughly with 1ml of dimethyl sulfoxide (DMSO) in separate tubes. Subsequently, 10µl of the prepared solution was analyzed using scanning electron microscopy (SEM) was conducted at magnifications ranging from500X to 80,800X, while X-ray diffraction (XRD) was performed at 2ɵ values between10–90 for characterization purposes. Antimicrobial activity assays involved loading sterilized nutrient agar and potato dextrose agar (PDA) with 100µl of Gram-positive bacteria, Gram-negative bacteria, and fungal organisms using the disc diffusion method. Zinc nanoparticles exhibited antibacterial activity against Gram-positive bacterium Clostridium perfringens, Gram-negative bacteria Aeromonas hydrophila, as well as fungi Candida albicans. These also shows antioxidant and antiproliferating activity.