Immediate Effect Of High-Frequency Chest Wall Compression On Oxygen Saturation And Minute Ventilation In Patients With Pulmonary Fibrosis

Abstract

Pulmonary fibrosis is a chronic, progressive interstitial lung disease marked by lung scarring, impaired gas exchange, and reduced lung compliance. Despite advancements in therapeutic options, managing pulmonary fibrosis remains challenging. This study explores the immediate effects of high-frequency chest wall vibration (HFCWV) on oxygen saturation (SpO₂) and minute ventilation in patients with pulmonary fibrosis. Using a pre-and-post experimental design, 40 participants received a single 20-minute session of HFCWV. Results demonstrated significant increases in SpO₂ (mean increase of 3%) and minute ventilation (mean increase of 0.7 L/min). Cardiovascular parameters, including heart rate and respiratory rate, remained stable, underscoring the safety of the intervention. These findings suggest that HFCWV may serve as an effective adjunct therapy in pulmonary rehabilitation programs. Further studies are recommended to evaluate long-term outcomes and its integration into clinical practice.