A Review On Nutrigenomics And Metabolic Diseases

Abstract

Nutrigenomics can be described as the science of tomorrow. It is a seminal field that can bring about the future of disease prevention and treatment. It would create advancements in nutrition and medicine. With the elaborate researches and substantial resources that future will be possible faster than you can imagine. This review article explores application of the concepts of nutrigenomics in etiological studies of metabolic diseases. While metabolic diseases have several causes such as age, lifestyle, overweight and disrupted insulin

metabolism; recessive genetic mutations are one of the prime causes. Many Genome-Wide Association studies have given insights into phenotypes, their biology and heritability and calculates their correlation to biomolecules absorbed from food. By isolating the factors that cause the genetic variation in an individual that makes them prone to develop metabolic diseases like obesity, cardiovascular diseases and type 2 diabetes, scientists can also formulate a counter mechanism that would account for the variability. Nutrients and bioactive molecules can be both a catalyst that can cause certain mutations or the ones that instigate the health effect. The genetics of each disease originating from metabolic disorder is different.

With accurate genetic information and biochemical analysis targeted dietary interventions can be formulated for individuals in order to prevent, treat or even eradicate these disorders.