Association Between B Vitamins, Anxiety And Stress (B-VITAAS): A Systematic Review

Abstract

Aims and objectives: The main aim and objective of the study is to conduct a systematic literature review on vitamin B complex deficiency and how it's linked with anxiety and stress, with recent findings.

Method: An extensive search strategy was done to systematically recognize the studies on the association of B vitamin deficiency with stress and anxiety by using a controlled keyword. An electronic search was conducted on 8^th March 2022 by using the search engines Google Scholar and PubMed, reviewing all the published articles in English, and there was no limitation for searching the articles such as study design, area, and any period frame.

Result: In starting the search engine picked out 1217 articles, of which 765 articles were from Google Scholar, 310 from PubMed, and 142 records from additional sources. A total of 949 studies were originated after removing the 268 duplicates. Based on the proper title and abstract, a further 210 full-text articles were found. This further excluded 182 studies based on the inclusion-exclusion criteria and finally generated 28 full-text papers for the systematic review. 

Conclusion: The literature search it concluded that vitamin B and its supplementation played an important role in improving the status of the deficient group. Its proper dosage and fortification improved the depression and anxiety symptoms. The B group vitamins especially biotin is linked to lowering the pervasiveness of anxiety, stress, and depression symptoms.