Phytopharmacognostical And Pharmacological Evaluation Of Amaranthus Caudatus Seeds Against Staphylococcus Aureus And Salmonella Typhi

Abstract

This research explores the potential antibacterial efficacy of Amaranthus caudatus seeds against two prominent bacterial strains, Staphylococcus aureus and Salmonella typhi. Given the rising concern of antibiotic resistance, there is a pressing need to explore alternative sources of antibacterial agents. Amaranthus caudatus, commonly known as love-lies-bleeding or tassel flower, has been historically recognized for its medicinal properties. However, its antibacterial potential against clinically relevant pathogens remains relatively underexplored. Soxhlet extraction method has been considered as the most efficient extraction method due to its ability to provide the high yield. Methanol and distilled water were used as the solvent for the extraction of Amaranthus caudatus seeds and it was found that methanolic extract have the higher yield in comparison to the aqueous yield. Due to the presence of phytochemicals like, flavonoids, terpenoids, alkaloids, and phenolic compounds, the plant shows the anti-bacterial activity. During the measurement of zone of inhibition, both the extracts showed greater activity towards the Salmonella typhi in comparison to the Staphylococcus aureus. And 20% concentration was found to be Minimum inhibitory concentration. Through a series of experimental approaches, this study aims to elucidate the antibacterial activity of Amaranthus caudatus seeds and provide insights into its mechanism of action against Staphylococcus aureus and Salmonella typhi.